We will prepare a chemical compound, aspirin, from its primitive compounds. We will also discuss its importance and the importance of preparing aspirin. This is a fascinating chemistry experiment because it combines organic chemistry with medical applications. Aspirin (acetylsalicylic acid) is manufactured from salicylic acid and acetic acid (or acetic anhydride) in the presence of sulfuric acid or phosphoric acid as a catalyst. Aspirin preparation (acetylsalicylic acid) Raw materials: Salicylic acid Acetic anhydride Sulfuric acid (catalyst) distilled water Reaction mechanism: The reaction is esterification of the hydroxyl group of salicylic acid by acetic anhydride, resulting in the formation of an acetyl ester and the release of acetic acid as a byproduct. 1. Salicylic acid reacts with acetic anhydride. 2. Sulfuric acid breaks the bond in acetic anhydride, which helps the hydroxyl group in salicylic acid react with the acetic group. 3. Acetylsalicylic acid (aspirin) is formed with the release of acetic acid. The importance of aspirin: As a pain reliever and antipyretic anti-inflammatory It is used to prevent blood clots and heart disease.